{"product_id":"numelvi-atinvicitinib-21-6mg-large-x-90-tablets","title":"Numelvi (Atinvicitinib) 21.6mg (Large) x 90 tablets","description":"\u003cp\u003ePetPA is proud to offer Numelvi Tablets, a prescription medicine containing \u003cstrong\u003eatinvicitinib\u003c\/strong\u003e, from manufacturer MSD Animal Health (Merck).\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003ePrescription medicine:\u003c\/strong\u003e This is a prescription medicine. Please ensure that you have read our \u003ca href=\"https:\/\/yourpetpa.com.au\/pages\/online-pet-pharmacy\"\u003e\u003cstrong\u003ePharmacy Information Page\u003c\/strong\u003e\u003c\/a\u003e before ordering this item. We require you to upload your veterinary prescription and post us the original. You will need to send your prescription to:\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003ePetPA Pharmacy\u003c\/strong\u003e\u003cbr\u003e\u003cstrong\u003eReply Paid 91355\u003c\/strong\u003e\u003cbr\u003e\u003cstrong\u003eElanora QLD 4221\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eActive Ingredients:\u003c\/strong\u003e Each tablet contains atinvicitinib 21.6mg.\u003c\/p\u003e\n\u003cp\u003eAvailable strengths include 4.8mg, 7.2mg, 21.6mg and 31.6mg.\u003c\/p\u003e\n\u003ch3\u003eCommonly asked questions about Numelvi:\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eWhat are Numelvi Tablets?\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eNumelvi is a prescription medication for dogs that helps control itching associated with allergic skin conditions, including atopic dermatitis. It contains atinvicitinib, a selective Janus kinase 1 (JAK1) inhibitor that works by blocking specific signalling pathways involved in itching, inflammation and allergic reactions.\u003c\/p\u003e\n\u003cp\u003eUnlike corticosteroids and antihistamines, Numelvi works by selectively targeting JAK1 enzymes involved in the body's inflammatory and allergic responses.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhy do dogs use Numelvi?\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eNumelvi is used to treat itching associated with allergic dermatitis and the clinical signs of atopic dermatitis in dogs. It helps reduce itching and inflammation associated with allergic skin conditions.\u003c\/p\u003e\n\u003cp\u003eNumelvi is designed for once-daily administration and should be given with food or around feeding time, as directed by your veterinarian.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhat problems could my dog have with Numelvi?\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eThe most commonly reported side effects include:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cp\u003eVomiting\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eDiarrhoea\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eLethargy\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eReduced appetite\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eAs Numelvi affects immune signalling pathways, your veterinarian should be informed of any existing infections, immune system conditions or other medications your dog is taking.\u003c\/p\u003e\n\u003cp\u003eThe safety of Numelvi has not been established in pregnant or lactating dogs or dogs intended for breeding. Safety has also not been investigated in dogs younger than six months of age.\u003c\/p\u003e\n\u003cp\u003eContact your veterinarian if you notice any unusual changes or side effects after starting treatment.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHow do you use Numelvi?\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eFollow the dosage instructions provided by your veterinarian. Numelvi is administered orally once daily, preferably with food or around feeding time.\u003c\/p\u003e\n\u003cp\u003eThe recommended dose in the UK product information is 0.8–1.2mg of atinvicitinib per kilogram of body weight, with tablet strength and quantity determined by the dog's weight.\u003c\/p\u003e\n\u003cp\u003eWash your hands thoroughly with soap and water immediately after handling the medication.\u003c\/p\u003e\n\u003cp\u003eYour veterinarian will determine the appropriate treatment duration based on your dog's individual needs and response to treatment.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhat is in Numelvi?\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eThe active ingredient in Numelvi is \u003cstrong\u003eatinvicitinib\u003c\/strong\u003e, a selective Janus kinase 1 (JAK1) inhibitor.\u003c\/p\u003e\n\u003cp\u003eAtinvicitinib works by inhibiting specific cytokines involved in itching, inflammation and allergic reactions. It is designed to target JAK1 more selectively than other JAK inhibitors, helping to manage the symptoms associated with allergic skin conditions.\u003c\/p\u003e\n\u003ch4\u003e\u003cspan style=\"font-weight: 400;\"\u003eRecommended related products:\u003c\/span\u003e\u003c\/h4\u003e\n\u003cul\u003e\n\u003cli style=\"font-weight: 400;\"\u003e\u003ca href=\"https:\/\/yourpetpa.com.au\/search?type=product%2Cpage\u0026amp;options%5Bprefix%5D=last\u0026amp;q=Bravecto\" title=\"Bravecto products for pets\"\u003e\u003cspan style=\"font-weight: 400;\"\u003eBravecto Chewables\u003c\/span\u003e\u003c\/a\u003e\u003c\/li\u003e\n\u003cli style=\"font-weight: 400;\"\u003e\u003ca href=\"https:\/\/yourpetpa.com.au\/search?type=product%2Cpage\u0026amp;options%5Bprefix%5D=last\u0026amp;q=NexGard%20Spectra\"\u003e\u003cspan style=\"font-weight: 400;\"\u003eNexGard Spectra\u003c\/span\u003e\u003c\/a\u003e\u003c\/li\u003e\n\u003cli style=\"font-weight: 400;\"\u003e\u003ca href=\"https:\/\/yourpetpa.com.au\/search?type=product%2Cpage\u0026amp;options%5Bprefix%5D=last\u0026amp;q=Simparica%20Trio\"\u003e\u003cspan style=\"font-weight: 400;\"\u003eSimparica Trio\u003c\/span\u003e\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp class=\"shaded\"\u003e\u003cem\u003e\u003cstrong\u003e\u003cspan style=\"text-decoration: underline;\"\u003ePlease note:\u003c\/span\u003e \u003c\/strong\u003eAustralian legislation prohibits the advertisement of prescription drugs to consumers; therefore, we are unable to display any images of the packaging or provide you with more information regarding this prescription medicine. All prescription medicines on the PetPA website are purchased through Veterinary Wholesalers; the same as those used by your Vet. Please \u003ca title=\"contact Your PetPA\" href=\"https:\/\/yourpetpa.com.au\/pages\/contact\"\u003ecall or email us\u003c\/a\u003e if you have any queries about any of the products on our site.\u003c\/em\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003ePetPA is committed to providing you with high-quality pet care products. Order Zenrelia Tablets today to help alleviate your dog's symptoms of allergic and atopic dermatitis. \u003c\/span\u003e\u003cem\u003e\u003cbr\u003e\u003c\/em\u003e\u003c\/p\u003e","brand":"MSD Animal Health","offers":[{"title":"Default Title","offer_id":67958124806326,"sku":"NUML90","price":291.95,"currency_code":"AUD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0579\/5712\/2230\/files\/PetPA_Prescription_Medication_Tablets.png?v=1778655485","url":"https:\/\/yourpetpa.com.au\/products\/numelvi-atinvicitinib-21-6mg-large-x-90-tablets","provider":"PetPA","version":"1.0","type":"link"}